Rönnblom A, Forsberg H, Danielsson A
Dept. of Medicine, Central Hospital, Boden, Sweden.
Scand J Gastroenterol. 1996 Jul;31(7):654-7. doi: 10.3109/00365529609009145.
Gastrointestinal complaints may be the initial symptom in myotonic dystrophy (MD). However, the frequency of gastrointestinal symptoms has never been prospectively evaluated.
Forty patients with MD were interviewed with regard to their GI symptoms with a standardized questionnaire. A group of healthy subjects matched for age and sex served as controls.
The most prevalent symptoms were abdominal pain (55%), dysphagia (45%), emesis (35%), chronic or episodic diarrhoea (33%), coughing while eating (33%), and anal incontinence (30%). Twenty-five per cent of the patients considered their GI problems to be the most disabling consequence of the disease, and 28% had GI problems that started before the diagnosis of MD.
GI symptoms are common in patients with MD, may be the initial symptoms, and are often considered to be the most disabling consequence of the disease.
胃肠道不适可能是强直性肌营养不良（MD）的首发症状。然而，胃肠道症状的发生率从未得到前瞻性评估。
采用标准化问卷对40例MD患者进行胃肠道症状访谈。选取一组年龄和性别匹配的健康受试者作为对照。
最常见的症状为腹痛（55%）、吞咽困难（45%）、呕吐（35%）、慢性或间歇性腹泻（33%）、进食时咳嗽（33%）和肛门失禁（30%）。25%的患者认为其胃肠道问题是该疾病最致残的后果，28%的患者在MD诊断之前就出现了胃肠道问题。
胃肠道症状在MD患者中很常见，可能是首发症状，且常被认为是该疾病最致残的后果。
