Hermann B P, Seidenberg M, Schoenfeld J, Peterson J, Leveroni C, Wyler A R
Department of Neurology, University of Wisconsin Medical Center, Madison 53792, USA.
Epilepsia. 1996 Oct;37(10):942-50. doi: 10.1111/j.1528-1157.1996.tb00531.x.
We assessed test-retest neuropsychological performance in patients with complex partial seizures to derive reliable change indices (RCIs) and regression-based norms for change, indices that may be helpful in assessing cognitive outcome after anterior temporal lobectomy.
Forty patients with complex partial seizures (CPS) who did not undergo epilepsy surgery were administered a comprehensive neuropsychological battery on two occasions. Their test-retest data were used to compute both RCIs and regression-based norms for change for each neuropsychological index. RCIs corrected for practice effects provide a confidence interval (CI) indicating the degree of performance change required to exceed the variability attributable to sources of error (e.g., practice, test-retest reliability). Regression-based norms for change also correct for several sources of measurement error and examine observed versus expected test-retest changes on a common metric, thereby facilitating determination of the degree and relative magnitude of change across cognitive domains.
Mean changes in test-retest performance were generally modest, but were evident across several test measures. Our data indicate a considerable degree of individual variability in test-retest performance.
RCIs and regression-based norms are complementary indexes and can be particularly useful in examining the test-retest performance of individual patients who undergo epilepsy surgery as well as in the more general investigation of cognitive outcome after epilepsy surgery.
我们评估了复杂部分性发作患者的重测神经心理学表现，以得出可靠变化指数（RCI）和基于回归的变化规范，这些指数可能有助于评估颞叶前部切除术后的认知结果。
40例未接受癫痫手术的复杂部分性发作（CPS）患者接受了两次全面的神经心理学测试。他们的重测数据用于计算每个神经心理学指标的RCI和基于回归的变化规范。针对练习效应进行校正的RCI提供了一个置信区间（CI），表明超过因误差来源（如练习、重测信度）导致的变异性所需的表现变化程度。基于回归的变化规范也校正了多个测量误差来源，并在一个通用指标上检查观察到的与预期的重测变化，从而便于确定认知领域变化的程度和相对大小。
重测表现的平均变化通常较小，但在多项测试中很明显。我们的数据表明重测表现存在相当程度的个体差异。
RCI和基于回归的规范是互补的指标，在检查接受癫痫手术的个体患者的重测表现以及更广泛地研究癫痫手术后的认知结果方面可能特别有用。
