Marder S R
West Los Angeles Veterans Affairs Medical Center, Brentwood Division, CA 90073, USA.
J Clin Psychiatry. 1996;57 Suppl 9:57-61.
Recent clinical experiences with risperidone including controlled trials, clinical observations, and reports of side effects are reviewed. The controlled trials indicate that risperidone is an effective anti-psychotic that may have advantages over conventional antipsychotics for treating both positive and negative symptoms of schizophrenia. A number of clinical reports indicate that risperidone is also effective for psychotic illnesses that result from other disorders. Risperidone has a relatively mild side effect profile when compared with conventional antipsychotics.
本文回顾了利培酮近期的临床经验,包括对照试验、临床观察及副作用报告。对照试验表明,利培酮是一种有效的抗精神病药物,在治疗精神分裂症的阳性和阴性症状方面可能优于传统抗精神病药物。一些临床报告表明,利培酮对其他疾病引起的精神病性障碍也有效。与传统抗精神病药物相比,利培酮的副作用相对较轻。