Deodhar A, Norden J, So Y, Bennett R
Division of Arthritis and Rheumatic Diseases, Oregon Health Sciences University, Portland 97201-3098, USA.
J Rheumatol. 1996 Jul;23(7):1292-4.
The association of systemic lupus erythematosus (SLE) and myasthenia gravis is well known. However, the association between SLE and Lambert-Eaton myasthenic syndrome (LEMS) is described in only 2 cases. We describe the case of a 31-year-old woman with SLE who presented with severe, predominantly proximal muscle weakness of subacute onset. The diagnosis of LEMS was based on her distinctive clinical and electrophysiological findings. She was treated successfully with plasmapheresis and oral prednisone. She remains in remission 6 months after this episode.
系统性红斑狼疮（SLE）与重症肌无力之间的关联已广为人知。然而，SLE与兰伯特-伊顿肌无力综合征（LEMS）之间的关联仅在2例病例中有所描述。我们报告一例31岁患有SLE的女性，她出现了亚急性起病的严重、主要为近端肌肉无力的症状。LEMS的诊断基于其独特的临床和电生理表现。她通过血浆置换和口服泼尼松成功治愈。此次发作6个月后她仍处于缓解期。
