Casley-Smith J R, Casley-Smith J R
Henry Thomas Laboratory (Microcirculation Research), University of Adelaide, Australia.
Lymphology. 1996 Jun;29(2):76-82.
Using previously presented data, from an open multi-centered trial, the Medians and Third Quartiles were calculated for the overall edema reductions the "average" patient received from an "average" therapist using Complex Physical Therapy (CPT) on 628 lymphedematous limbs. These data provide therapists and patients a general guideline as to the minimal reductions which can be expected in three quarters of patients from average therapists, using CPT with or without the administration of benzo-pyrones. Benzo-pyrones were considered separately: oral (given for three months before and for 11 months after the course of CPT) and topical (during and after CPT). Depending on which measure of edema and its alterations were used, these reductions increased those from CPT alone from 130% to 200% and, after one year, between 150% to 300%. Whereas the effects of oral and topical benzo-pyrones were not statistically different, their combined usage was more effective than use of either alone.
利用一项开放多中心试验中先前公布的数据，计算了628例淋巴水肿肢体患者接受“普通”治疗师采用综合物理治疗（CPT）后总体水肿减轻情况的中位数和第三四分位数。这些数据为治疗师和患者提供了一个大致的指导方针，即使用或不使用苯并吡喃类药物进行CPT治疗时，普通治疗师治疗的四分之三患者预计可达到的最小水肿减轻程度。苯并吡喃类药物被分别考虑：口服（在CPT疗程前三个月和疗程后11个月给药）和局部用药（在CPT期间及之后）。根据所使用的水肿测量方法及其变化情况，这些水肿减轻程度使仅采用CPT治疗时的减轻程度提高了130%至200%，一年后提高了150%至300%。虽然口服和局部使用苯并吡喃类药物的效果在统计学上没有差异，但它们联合使用比单独使用任何一种更有效。
