Casley-Smith J R, Casley-Smith J R, Curri S, Földi M
Henry Thomas Lab, University of Adelaide, Australia.
Lymphology. 1993 Mar;26(1):25-7.
A new reversible complex between troxerutin and phosphatidylcholine (85-90mg/kg per day), in the form of a liposome-like water microdispersion, was topically applied to the rat thigh in an experimental counterpart of acute lymphedema. After four days there was 75% less hindlimb edema (mean decrease 40% of normal compared to control 10% of normal) in the treated compared with the untreated rats. These findings suggest that this drug preparation may be useful to minimize acute peripheral lymphedema in patients.
