Chawla S K, Missri J, Wessel R
Department of Surgery, St. Francis Hospital and Medical Center, Hartford, USA.
Conn Med. 1996 Aug;60(8):455-60.
Ninety consecutive patients underwent mitral valve repair for mitral regurgitation (MR) utilizing intraoperative transesophageal echocardiography (TEE). Fifty-nine males and 31 females between the ages of 31 and 88 with a mean age of 67.9 years were evaluated. Preoperative TEE demonstrated pathology involving the posterior leaflet in 28 patients, anterior leaflet in 21 patients, both leaflets in 19 patients, annular dilatation in 19 patients, and restricted leaflet in three patients. Surgical procedures attempted included quadrangle resection of posterior leaflet pathology (40), Duran "flip over" operation (13), or Goretex suture for anterior leaflet pathology (20), and ring alone for central/ischemic mitral regurgitation (20). TEE immediately following repair showed either no regurgitation or a trace in 78 patients (86%). Time elapsed since repair ranged from one month to 55 months, with a mean of 29 months. Long-range evaluation of mitral valve competence was done by clinical examination and transthoracic or transesophageal echocardiography. Three patients died postoperatively. Fifty-six of 87 patients (64%) had either no or trivial MR within the first year of follow-up. Ring alone for annular dilatation and Goretex suture for anterior leaflet prolapse had the highest incidence of progression of MR. Among the 65 patients followed over one year, 42 (64%) continue to have either none or trivial MR. Three patients had worsening MR requiring mitral valve replacement. Quadrangle resection for posterior leaflet repair and Duran "flip over" operation for anterior leaflet pathology had the highest success rate in long-term follow-up.
连续90例二尖瓣反流(MR)患者接受了术中经食管超声心动图(TEE)引导下的二尖瓣修复术。评估了59例男性和31例女性,年龄在31至88岁之间,平均年龄为67.9岁。术前TEE显示,28例患者病变累及后叶,21例累及前叶,19例累及双叶,19例存在瓣环扩张,3例存在瓣叶受限。尝试的手术方式包括后叶病变四边形切除术(40例)、杜兰“翻转”手术(13例)、前叶病变戈尔特斯缝线修复术(20例)以及单纯瓣环成形术治疗中心性/缺血性二尖瓣反流(20例)。修复术后即刻TEE显示,78例患者(86%)无反流或仅有微量反流。修复术后时间间隔从1个月至55个月不等,平均为29个月。通过临床检查以及经胸或经食管超声心动图对二尖瓣功能进行长期评估。3例患者术后死亡。87例患者中有56例(64%)在随访的第一年内无反流或仅有微量反流。单纯瓣环成形术治疗瓣环扩张以及戈尔特斯缝线修复术治疗前叶脱垂的MR进展发生率最高。在随访超过1年的65例患者中,42例(64%)持续无反流或仅有微量反流。3例患者MR恶化,需要进行二尖瓣置换术。后叶修复的四边形切除术以及前叶病变的杜兰“翻转”手术在长期随访中成功率最高。