Brunskill E W, Bayles K W
Program in Molecular and Cell Biology, University of Maryland, Baltimore County 21228, USA.
J Bacteriol. 1996 Oct;178(19):5810-2. doi: 10.1128/jb.178.19.5810-5812.1996.
In this report, the characterization of a Staphylococcus aureus operon containing two LytSR-regulated genes, lrgA and lrgB, is described. Sequence and mutagenesis studies of these genes suggest that lrgA encodes a murein hydrolase exporter similar to bacteriophage holin proteins while lrgB may encode a protein having murein hydrolase activity.
在本报告中,描述了一个含有两个受LytSR调控基因lrgA和lrgB的金黄色葡萄球菌操纵子的特征。对这些基因的序列和诱变研究表明,lrgA编码一种类似于噬菌体穿孔素蛋白的胞壁质水解酶输出蛋白,而lrgB可能编码一种具有胞壁质水解酶活性的蛋白。