Mosser D M, Hondalus M K
Dept of Microbiology and Immunology, Temple University School of Medicine, Philadelphia, PA 19140, USA.
Trends Microbiol. 1996 Jan;4(1):29-33. doi: 10.1016/0966-842x(96)81502-2.
Rhodococcus equi is emerging as a cause of pneumonia in immunocompromised people, especially those with AIDS. Like mycobacteria, R. equi is phagocytosed by alveolar macrophages and replicates within them. Recent work is beginning to elucidate the cell and molecular biology of this opportunistic pathogen and the host immune response to it.
马红球菌正逐渐成为免疫功能低下人群,尤其是艾滋病患者肺炎的病因。与分枝杆菌一样,马红球菌被肺泡巨噬细胞吞噬并在其中繁殖。最近的研究开始阐明这种机会性病原体的细胞和分子生物学以及宿主对它的免疫反应。