Kurtzke J F
Neuroepidemiology Research Program, Department of Veterans Affairs Medical Center, Washington, DC, USA.
Neurol Clin. 1996 May;14(2):255-72. doi: 10.1016/s0733-8619(05)70255-3.
Neuroepidemiology is the application of the methods of epidemiology to the problems of clinical neurology. After diagnosis, the most basic characterization of a disease is its frequency. This characterization requires ascertainment of case (numerator) within their population at risk (denominator) to provide incidence, prevalence, and mortality rates. Mortality rates come from government publications, and morbidity rates (incidence and prevalence) from specific field surveys. Definition of the course of illness and identification of risk factors for occurrence or course require specific studies and appropriate statistical testing.
神经流行病学是将流行病学方法应用于临床神经病学问题的学科。疾病诊断后,其最基本的特征是发病率。这种特征需要确定其危险人群中的病例数(分子),以提供发病率、患病率和死亡率。死亡率来自政府出版物,发病率(发病率和患病率)来自特定的现场调查。对疾病病程的定义以及对发病或病程危险因素的识别需要进行特定的研究和适当的统计检验。