Donnelly P
Department of Statistics, University of Chicago, IL 60637, USA.
Ciba Found Symp. 1996;197:25-40; discussion 40-50. doi: 10.1002/9780470514887.ch3.
Data from different individuals at a single locus are positively correlated because of the shared genealogy of the sampled genes. This paper illustrates the qualitative effects on genealogical trees of assumptions about population demography, and it considers the consequences for genetic variability. An understanding of these effects is invaluable in the interpretation of data and for inferences about population history. In contrast, traditional genetic measures of diversity and approximation methods do not seem well suited for addressing the problem.
由于抽样基因的共同谱系，单个基因座上来自不同个体的数据呈正相关。本文阐述了关于种群人口统计学假设对谱系树的定性影响，并探讨了其对遗传变异性的影响。理解这些影响对于数据解释和种群历史推断具有重要价值。相比之下，传统的遗传多样性测量方法和近似方法似乎不太适合解决这个问题。
