Kalaska J F
Département de physiologie, Faculté de médecine, Université de Montréal, OC, Canada.
Can J Physiol Pharmacol. 1996 Apr;74(4):483-98.
For years, area 5 of the parietal cortex was thought to be a somatic sensory structure. This view was challenged by recordings during active movements in alert behaving monkeys, which suggested that area 5 also contained populations of neurons that issued nonspecific, context-dependent "commands" about intended motor responses. Recent studies have revealed that area 5 generates a representation of the spatiotemporal form of arm movements and arm postures, although the parameter space of that representation is still controversial. They also showed that many area 5 cells are recipient to centrally generated signals about the motor relevance of external sensory signals. These new results support the hypothesis that area 5 contributes to the sensorimotor guidance of motor behavior, by contributing to the somatomotor and visuomotor transformations presumed to underlie visually guided behavior. However, area 5 appears to be less directly implicated than the premotor cortex in the process of selecting the nature of the response to instructional signals.
多年来，顶叶皮质的5区一直被认为是一个躯体感觉结构。这种观点受到了对清醒行为猴子进行主动运动时记录结果的挑战，这些记录表明5区还包含一些神经元群体，它们会发出关于预期运动反应的非特异性、依赖于上下文的“指令”。最近的研究表明，5区会生成手臂运动和手臂姿势的时空形式的表征，尽管该表征的参数空间仍存在争议。这些研究还表明，许多5区的细胞会接收来自中枢的关于外部感觉信号运动相关性的信号。这些新结果支持了这样一种假设，即5区通过参与被认为是视觉引导行为基础的躯体运动和视觉运动转换，从而有助于运动行为的感觉运动引导。然而，在选择对指令信号的反应性质的过程中，5区似乎没有运动前皮质那么直接地参与其中。
