Woods C A, Efron N
Department of Optometry and Vision Sciences, UMIST, Manchester, England.
CLAO J. 1996 Jul;22(3):172-8.
While the benefits of planned replacement of soft contact lenses have been investigated, the question of whether there are any clinical benefits to planned replacement of rigid gas permeable (RGP) lenses does not appear to have been addressed experimentally. We aimed to determine the benefits of regular replacement of extended wear RGP contact lenses.
We conducted a prospective, single-center, controlled, double-masked study of 39 RGP lens wearers. The subjects were divided into two groups and wore extended wear Quantum 2 lenses (Dk = 120) for 12 months. Subjects in Group I replaced lenses every 3 months, whereas those in Group II were not scheduled to replace their lenses. The integrity of the lenses and the ocular responses to lens wear were monitored in both groups every three months.
Compared to lenses worn by subjects in Group I, lenses worn by Group II subjects showed significantly more mucous coating, lens binding, and corneal staining over time (P < 0.05; ANCOVA). There was no difference in microcystic or tarsal conjunctiva response, lens comfort, refractive change, or visual acuity between the two groups.
We advocate that to maintain optimal lens integrity and ocular health, RGP lenses used for extended wear should be replaced every 3 to 6 months.
虽然已对软性隐形眼镜计划性更换的益处进行了研究，但硬性透气性（RGP）镜片计划性更换是否具有临床益处这一问题似乎尚未通过实验得到解决。我们旨在确定定期更换长戴型RGP隐形眼镜的益处。
我们对39名RGP镜片佩戴者进行了一项前瞻性、单中心、对照、双盲研究。受试者被分为两组，佩戴长戴型Quantum 2镜片（Dk = 120）12个月。第一组受试者每3个月更换一次镜片，而第二组受试者未安排更换镜片。两组均每三个月监测镜片的完整性以及眼部对镜片佩戴的反应。
与第一组受试者佩戴的镜片相比，随着时间推移，第二组受试者佩戴的镜片出现明显更多的黏液覆盖、镜片黏附以及角膜染色（P < 0.05；协方差分析）。两组在微囊肿或睑结膜反应、镜片舒适度、屈光变化或视力方面无差异。
我们主张，为保持最佳的镜片完整性和眼部健康，用于长戴的RGP镜片应每3至6个月更换一次。
