Jones L, Woods C A, Efron N
Biomaterials Research Unit, Aston University, Birmingham, United Kingdom.
CLAO J. 1996 Oct;22(4):258-61.
The purpose of this study was to evaluate the life expectancy of various rigid gas permeable (RGP) lens materials used on a daily wear basis and to compare these results with the life expectancy of a matched group of soft lens wearers.
We retrospectively analyzed the records of 600 contact lens wearing patients (300 soft contact lens users and 300 RGP lens users fit between September 1987 and September 1994. None of the subjects wore lenses on a planned replacement system. For the purpose of the study, RGP lenses were divided into three groups: < or = 40 Dk were considered low-Dk; 41-89 Dk were considered mid-Dk; and > or = 90 Dk were considered high-Dk. All soft lenses were high water content lenses (> or = 60% water content). Lenses were included if they were replaced due to loss, breakage, deposition, or poor wettability but not if replaced because of changes in fit or prescription.
The mean (+/- SD) life-spans of each lens type in months were 19.9 +/- 17 for low-Dk RGP lenses, 15.9 +/- 13.3 for mid-Dk RGP lenses, 9.0 +/- 8.2 for high-Dk RGP lenses, and 6.4 +/- 5.2 for high water content soft lenses. Statistical analysis using a one-way ANOVA on ranks indicated that these results were statistically significant (P < 0.0001).
Patients should be informed that high-Dk lenses (RGP and soft) provide substantial clinical benefits and that they should except to replace high-Dk RGP lenses after approximately 6 months. This lends further credence to the use of high-Dk lenses on a planned replacement basis.
本研究旨在评估日常佩戴的各种硬性透气性(RGP)镜片材料的使用寿命,并将这些结果与一组相匹配的软性镜片佩戴者的使用寿命进行比较。
我们回顾性分析了1987年9月至1994年9月期间600名佩戴隐形眼镜患者的记录(300名软性隐形眼镜使用者和300名RGP镜片使用者)。所有受试者均未采用计划更换系统佩戴镜片。为了本研究的目的,RGP镜片被分为三组:Dk≤40被视为低Dk;41 - 89 Dk被视为中Dk;Dk≥90被视为高Dk。所有软性镜片均为高含水量镜片(含水量≥60%)。如果镜片因丢失、破损、沉积或润湿性差而被更换则纳入研究,但因适配性或处方改变而更换的则不纳入。
每种镜片类型以月为单位的平均(±标准差)使用寿命分别为:低Dk RGP镜片19.9±17,中Dk RGP镜片15.9±13.3,高Dk RGP镜片9.0±8.2,高含水量软性镜片6.4±5.2。使用秩次的单因素方差分析进行的统计分析表明,这些结果具有统计学意义(P < 0.0001)。
应告知患者,高Dk镜片(RGP和软性)具有显著的临床益处,并且他们应该预期在大约6个月后更换高Dk RGP镜片。这进一步证明了在计划更换的基础上使用高Dk镜片的合理性。