Richardson M G, Lee A C, Wissler R N
Department of Anesthesiology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA.
Reg Anesth. 1996 Mar-Apr;21(2):119-23.
A commonly used test dose in parturients receiving continuous lumbar epidural analgesia for labor consists of 3 mL of dextrose-free 1.5% lidocaine with 1:200,000 epinephrine.
of 1,962 obstetric epidural anesthetics administered over a 17-month period, unintentional subarachnoid placement of the epidural catheter was detected by injection of the test dose in five laboring patients. The characteristics of the resulting subarachnoid blocks were studied.
After negative aspiration for cerebrospinal fluid in each case, test dose injection resulted in the rapid onset of high sensory block with associated motor and sympathetic block, accompanied by significant hypotension requiring aggressive treatment.
While this test dose appears to be a sensitive indicator of an unexpected subarachnoid catheter, the resulting excessive spinal blocks in these laboring patients raise the question of its safety.
在接受连续腰段硬膜外分娩镇痛的产妇中,常用的试验剂量为3毫升不含葡萄糖的1.5%利多卡因加1:200,000肾上腺素。
在17个月期间实施的1962例产科硬膜外麻醉中,通过向5例分娩患者注射试验剂量检测到硬膜外导管意外置入蛛网膜下腔。对由此产生的蛛网膜下腔阻滞的特征进行了研究。
在每例脑脊液回抽阴性后,注射试验剂量导致高平面感觉阻滞迅速出现,并伴有运动和交感神经阻滞,同时伴有严重低血压,需要积极治疗。
虽然该试验剂量似乎是意外蛛网膜下腔置管的敏感指标,但这些分娩患者由此产生的过度脊髓阻滞引发了其安全性的问题。