Schnurr D, Bollen A, Crawford-Miksza L, Dondero M E, Yagi S
Viral and Rickettsial Disease Laboratory, California State Department of Health Services, Berkeley 94704, USA.
J Med Virol. 1995 Oct;47(2):168-71. doi: 10.1002/jmv.1890470210.
A mixture of adenoviruses 31 and 49 was isolated from the brain of an AIDS patient with encephalitis. Adenovirus hexon protein was detected in neurons by indirect immunofluorescence. By restriction endonuclease analysis both adenovirus 31 and 49 were shown to be new genotypes. This is the first report of the isolation of a mixture of adenoviruses from adenovirus encephalitis and the first association of adenovirus 49, a new candidate serotype, with encephalitis.
从一名患有脑炎的艾滋病患者大脑中分离出腺病毒31型和49型的混合物。通过间接免疫荧光法在神经元中检测到腺病毒六邻体蛋白。通过限制性内切酶分析表明,腺病毒31型和49型均为新基因型。这是首次从腺病毒性脑炎中分离出腺病毒混合物的报告,也是新候选血清型腺病毒49型与脑炎的首次关联报告。