La Rosa Giuseppina, Muscillo Michele, Iaconelli Marcello, Di Grazia Antonio, Fontana Stefano, Sali Michela, De Carolis Elena, Cattani Paola, Manzara Stefania, Fadda Giovanni
Istituto Superiore di Sanità, Dipartimento Ambiente e Connessa Prevenzione Primaria, Roma, Italy.
New Microbiol. 2006 Jul;29(3):177-84.
There is little information on the epidemiology of Human Adenoviruses (HAdVs) in Italy. In this study, 103 HAdV isolates, collected by the A. Gemelli Hospital (Catholic University Medical School of Rome, Italy) between 1987 and 2005, were genotyped by sequencing and phylogenetic analysis on a partial hexon gene region. Nine different serotypes belonging to all six HAdV species were identified. Serotype 2 was the most frequent (53.4%), followed by serotype 1 (15.53%) and serotype 41 (9.7%). Partial-hexon-based identification was confirmed as an effective tool for studying the molecular epidemiology of HAdVs.
关于意大利人类腺病毒（HAdVs）的流行病学信息很少。在本研究中，对1987年至2005年间由意大利罗马天主教大学医学院阿·杰梅利医院收集的103株HAdV分离株，通过对部分六邻体基因区域进行测序和系统发育分析进行基因分型。鉴定出属于所有六种HAdV物种的九种不同血清型。血清型2最为常见（53.4%），其次是血清型1（15.53%）和血清型41（9.7%）。基于部分六邻体的鉴定被确认为研究HAdVs分子流行病学的有效工具。
