Dubinskaia N I, Burlakova E B
Tsitologiia. 1977 Mar;19(3):329-33.
The highest increase in the mitotic index (MI) reticuloendothelial cells observed in the experiment after antioxidant treatment coincided in time with the maximal MI value of these cells in the untreated animals. However, the maximal increase of MI in hepatocytes took place when the minimal value of MI was registered in cells of the control animals. A significant increase in MI occurred both in hepatocytes and reticuloendothelial cells within the two first hours after antioxidant injection, but at this very time a more evident stimulation was observed for the hepatocytes. Antioxidant doses stimulating cell division produce similar effect on reticuloendothelial cells and hepatocytes, just reported here, as do tireoid ans steroid hormones.
实验中观察到，抗氧化剂处理后有丝分裂指数（MI）最高的增加出现在网状内皮细胞中，这与未处理动物中这些细胞的最大MI值在时间上是一致的。然而，肝细胞中MI的最大增加发生在对照动物细胞中MI记录到最小值的时候。抗氧化剂注射后的最初两小时内，肝细胞和网状内皮细胞的MI均显著增加，但此时观察到肝细胞受到的刺激更为明显。刺激细胞分裂的抗氧化剂剂量对网状内皮细胞和肝细胞产生的作用，正如这里所报道的，与甲状腺和类固醇激素产生的作用相似。
