[使用18F-FDG单光子发射计算机断层扫描进行肿瘤诊断]

[Tumor diagnosis using 18F-FDG SPECT].

作者信息

Sugiyama S, Suzuki Y, Matsuzaki H, Tomiyoshi K, Endo K

机构信息

Department of Radiology, Takasaki National Hospital.

出版信息

Nihon Igaku Hoshasen Gakkai Zasshi. 1996 Aug;56(9):679-80.

PMID:8831228

Abstract

Fluorine-18-fluorodeoxyglucose (18F-FDG) single photon emission CT(SPECT) imaging was performed in four patients with malignant neoplasms. Acquisition of SPECT was started 40 minutes after intravenous administration of 370MBq of 18F-FDG using dual-headed gamma camera equipped with 511keV collimators. Whole body planar scintigraphy was also obtained after the SPECT study. Tumor uptake of 18F-FDG was detected in three of four patients on both SPECT and planar images, and a 2.5 x 1.5 cm lung tumor was clearly visualized on SPECT image. Excellent SPECT image of 18F-FDG using a conventional gamma camera system is promising for the wide use of this system in cancer diagnosis.

摘要

对4例恶性肿瘤患者进行了氟-18-氟脱氧葡萄糖（18F-FDG）单光子发射计算机断层扫描（SPECT）成像。静脉注射370MBq的18F-FDG后40分钟，使用配备511keV准直器的双头伽马相机开始采集SPECT图像。在SPECT检查后还获得了全身平面闪烁扫描图像。4例患者中有3例在SPECT和平面图像上均检测到18F-FDG的肿瘤摄取，并且在SPECT图像上清晰可见一个2.5×1.5cm的肺部肿瘤。使用传统伽马相机系统获得的18F-FDG的优质SPECT图像有望使该系统在癌症诊断中得到广泛应用。