Kelley C M, Cohen M B, Raab S S
Department of Pathology, University of Iowa Hospitals and Clinics, Iowa City 52242-1009, USA.
Diagn Cytopathol. 1996 Feb;14(1):14-9. doi: 10.1002/(SICI)1097-0339(199602)14:1<14::AID-DC4>3.0.CO;2-V.
Renal fine-needle aspiration biopsy (FNAB) is used in several clinical scenarios: in patients with classic radiographic lesions; in non-operable patients with presumed high stage disease; and in patients with radiographic problematic lesions. Although overall, FNAB is a sensitive test, its role in the latter two populations has not been clearly established. To investigate the utility of FNAB in these patients, we retrospectively evaluated 43 renal FNABs in regards to diagnostic accuracy and clinical outcome. FNAB diagnoses were: malignant (36), suspicious (6), and insufficient (1). Our results indicate: 1) renal FNAB is accurate in patients with high stage lesions; 2) FNAB is less accurate in patients with radiographic problematic lesions; 3) the FNAB diagnosis of malignant increases the post-FNAB probability of malignancy, whereas the diagnosis of suspicious decreases the probability; and 4) there is excellent correlation for nuclear grade. We conclude that renal FNAB is useful in evaluating renal masses.
肾细针穿刺活检（FNAB）用于多种临床情况：有典型影像学病变的患者；疑似晚期疾病的不可手术患者；以及有影像学疑难病变的患者。虽然总体而言，FNAB是一项敏感的检查，但它在后两类人群中的作用尚未明确确立。为了研究FNAB在这些患者中的效用，我们回顾性评估了43例肾FNAB的诊断准确性和临床结果。FNAB诊断结果为：恶性（36例）、可疑（6例）和不足（1例）。我们的结果表明：1）肾FNAB对晚期病变患者诊断准确；2）FNAB对有影像学疑难病变的患者诊断准确性较低；3）FNAB诊断为恶性会增加FNAB后恶性肿瘤的概率，而诊断为可疑则会降低该概率；4）核分级有极好的相关性。我们得出结论，肾FNAB在评估肾肿块方面有用。
