Sliutz G
Abteilung für Gynäkologie und Geburtshilfe, Universitäts-Frauenklinik, Wien.
Wien Med Wochenschr. 1996;146(1-2):14-7.
The prognosis in ovarian cancer remains poor, and there is a need to identify patients who are less likely to respond to treatment or are suffering from low stage disease and have a worse prognosis. Stage, presence of ascites, age of patient, histologic type and grade, as well as cellular DNA content or ploidy and mitotic activity index are of prognostic value. In addition to that halftime of CA 125 is also a prognostic indicator. Recently expression of receptors, growth factors and the expression of several oncogenes revealed to have a prognostic significance in ovarian cancer. An overview of the most important prognostic factors is presented.
卵巢癌的预后仍然很差，因此有必要识别那些对治疗反应较小或患有早期疾病且预后较差的患者。分期、腹水的存在、患者年龄、组织学类型和分级，以及细胞DNA含量或倍性和有丝分裂活性指数都具有预后价值。此外，CA 125的半衰期也是一个预后指标。最近发现，受体、生长因子的表达以及几种癌基因的表达在卵巢癌中具有预后意义。本文将对最重要的预后因素进行概述。
