Okada K, Kono N, Kobayashi S, Yamaguchi S
Internal Medicine III, Shimane Medical University, Izumo.
Intern Med. 1996 Jun;35(6):515-6. doi: 10.2169/internalmedicine.35.515.
A patient with a history of cerebrovascular disease, hypertension, and previous gastrectomy developed metabolic alkalosis and myoclonus. His medications included the anti-hypertensive agents nicardipine hydrochloride, delapril, prazosin; dihydroergotoxin and ticlopidine for cerebral infarction; estazolam for insomnia; azuren-L-glutamine compound and S-M powder. In addition, he had taken 12 grams per day of Ohta's Isan antacid, which contained 625 mg sodium bicarbonate per 1.3 g of antacid powder over a 6-month period. This antacid is commonly used in Japan. This is the first report of a case of metabolic alkalosis and myoclonus secondary to ingestion of a commercially available antacid in Japan.
一名有脑血管疾病、高血压病史且曾接受胃切除术的患者出现了代谢性碱中毒和肌阵挛。他的用药包括抗高血压药物盐酸尼卡地平、地拉普利、哌唑嗪；用于脑梗死的双氢麦角毒素和噻氯匹定；用于失眠的艾司唑仑；复方谷氨酰胺和S-M散剂。此外，他在6个月的时间里每天服用12克太田胃散抗酸剂，每1.3克抗酸剂粉末中含有625毫克碳酸氢钠。这种抗酸剂在日本常用。这是日本首例因摄入市售抗酸剂继发代谢性碱中毒和肌阵挛的病例报告。
