Keris V, Kasyanov V, Enina G
Latvian Neuroangiological Centre, Riga 7th Clinical Hospital, Latvia.
Acta Neurochir (Wien). 1996;138(6):752-8. doi: 10.1007/BF01411483.
Surgical treatment of vertebrobasilar circulation disorders includes percutaneous transluminal angioplasty more often recently. However, the biomechanical aspects of transluminal angioplasty have not been studied sufficiently so far. 148 left and right vertebral artery segments were taken from 24 autopsy subjects (14 male and 10 female) aged from 20 to 75, who had neither systemic nor cerebrovascular lesions. Biomechanical examination and experimental transluminal angioplasty (ETA) of the tubular segments of vertebral artery (VA) were carried out by the special equipment developed for this purpose. The data were obtained using telemetrical, morphometrical and hystological methods. The biomechanical properties taken in the conditioned physiological rate are different for each segment of the VA. The stiffness of VA wall increases with age (mainly after 40 years), particularly in segments V1 and V3. Nevertheless, after high intravascular pressure application the diameter response of VA to intravascular fluid pressure increases if sufficient structural damage of the arterial wall was made.
近年来，经皮腔内血管成形术在椎基底动脉循环障碍的外科治疗中应用更为频繁。然而，到目前为止，腔内血管成形术的生物力学方面尚未得到充分研究。从24名年龄在20至75岁之间、既无全身病变也无脑血管病变的尸检对象（14名男性和10名女性）身上获取了148条左右椎动脉节段。使用为此专门研制的设备对椎动脉（VA）的管状节段进行了生物力学检查和实验性腔内血管成形术（ETA）。数据通过遥测、形态测量和组织学方法获得。在条件生理速率下获取的生物力学特性因VA的每个节段而异。VA壁的刚度随年龄增加（主要在40岁以后），尤其是在V1和V3节段。然而，如果动脉壁受到足够的结构损伤，在施加高血管内压力后，VA对血管内流体压力的直径反应会增加。
