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胆管残余结石的处理:一项比较体外与体内碎石术的前瞻性开放试验

Management of retained bile duct stones: a prospective open trial comparing extracorporeal and intracorporeal lithotripsy.

作者信息

Adamek H E, Maier M, Jakobs R, Wessbecher F R, Neuhauser T, Riemann J F

机构信息

Department of Medicine C (Gastroenterology & Hepatology), Academic Hospital, University of Mainz, Ludwigshafen, Germany.

出版信息

Gastrointest Endosc. 1996 Jul;44(1):40-7. doi: 10.1016/s0016-5107(96)70227-4.

Abstract

BACKGROUND

Endoscopic management of common bile duct stones has become the approach of choice, especially in patients with high surgical risk. Problems are encountered if there are large stones or a duct stenosis. For these difficult stones, shock wave technology serves as an alternative to surgical intervention.

METHODS

A total of 125 patients with common bile duct stones in whom conventional endoscopic treatment had failed were selected and treated either by extracorporeal piezoelectric lithotripsy (ESWL, n = 79) or intracorporeal electrohydraulic lithotripsy (EHL, n = 46). The average age of our patients was 70 years.

RESULTS

In the ESWL group visualization of the stones by ultrasound and ensuing treatment were possible in 71 out of 79 patients (90%); stones could be fragmented in 68 patients. The biliary tree could then be completely freed of calculi in 62 of 79 patients, a success rate of 78.5%. In the EHL group, stones were successfully fragmented in 38 of 46 patients; 34 patients (74%) eventually became stone free. Thirty-day mortality was zero in both groups. Combined treatment including ESWL, EHL, and intracorporeal laser lithotripsy was finally successful in 118 patients (94%).

CONCLUSIONS

Endoscopic management in combination with the lithotripsy techniques described can be recommended as the method of choice for treating difficult common bile duct stones. A success rate of almost 100% and a mortality rate of 0% is now the established standard, even in elderly and unstable patients.

摘要

背景

胆总管结石的内镜治疗已成为首选方法,尤其是对于手术风险高的患者。如果存在大结石或胆管狭窄,则会遇到问题。对于这些难处理的结石,冲击波技术可作为手术干预的替代方法。

方法

选择125例常规内镜治疗失败的胆总管结石患者,采用体外压电碎石术(ESWL,n = 79)或体内液电碎石术(EHL,n = 46)进行治疗。我们的患者平均年龄为70岁。

结果

在ESWL组中,79例患者中有71例(90%)通过超声可观察到结石并随后进行了治疗;68例患者的结石被击碎。79例患者中有62例胆管内结石被完全清除,成功率为78.5%。在EHL组中,46例患者中有38例结石被成功击碎;34例患者(74%)最终结石清除。两组的30天死亡率均为零。包括ESWL、EHL和体内激光碎石术在内的联合治疗最终在118例患者(94%)中取得成功。

结论

内镜治疗结合所述的碎石技术可被推荐为难治性胆总管结石的首选治疗方法。即使在老年和不稳定患者中,近100%的成功率和0%的死亡率现在已成为既定标准。

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