Peters J A, Stopfer J E
Medical Genetics Branch, National Center for Human Genome Research, National Institutes of Health, Bethesda, Maryland, USA.
Oncology (Williston Park). 1996 Feb;10(2):159-66, 175; discussion 176-6, 178,.
Increased knowledge about inherited susceptibility for cancer and the identification of genes associated with cancer risk has increased the need for individuals with training in genetics to work closely with oncology professionals in the familial cancer arena. Genetic counselors can provide a variety of useful services: They may function as clinical coordinators of a family cancer risk counseling (FCRC) program and serve as study coordinatiors on research teams. In the oncology practice setting, genetic counselors who are trained to do cancer risk counseling can help ascertain and evaluate familial clusters of cancers. In the context of FCRC, the genetic counselor can educate family members about risk factors for cancer and the significance of a positive family history, assess psychosocial functioning and provide psychosocial support and referrals. Genetic susceptibility testing should be offered only with appropriate genetic counseling.
对癌症遗传易感性的了解增加以及与癌症风险相关基因的识别，使得在家族性癌症领域，需要有遗传学培训的人员与肿瘤学专业人员密切合作。遗传咨询师可以提供多种有用的服务：他们可以担任家族癌症风险咨询（FCRC）项目的临床协调员，并在研究团队中担任研究协调员。在肿瘤学实践环境中，经过癌症风险咨询培训的遗传咨询师可以帮助确定和评估家族性癌症聚集情况。在FCRC的背景下，遗传咨询师可以教育家庭成员了解癌症风险因素以及阳性家族史的意义，评估心理社会功能并提供心理社会支持和转诊建议。只有在进行适当的遗传咨询后，才应提供遗传易感性检测。
