[AMP system: longitudinal studies of psychopathologic and somatic symptoms. An empiric investigation of the problem of side effects (author's transl)].

The psychopathologic and somatic state of 681 psychiatric patients were investigated in longitudinal studies within the scope of different psychopharmacologic trials. Most psychologic symptoms occur less frequently, whereas somatic symptoms are found to increase, which suggests side effects from psychotropic drugs. The analyses show that the AMP-system can be reduced by 49 (possibly 45) symptoms, as initial findings and developments show that these symptoms are rare, and do not allow of differentiation between diagnostic groups.