Fleshner N E, Herr H W, Stewart A K, Murphy G P, Mettlin C, Menck H R
Department of Urology, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
Cancer. 1996 Oct 1;78(7):1505-13. doi: 10.1002/(sici)1097-0142(19961001)78:7<1505::aid-cncr19>3.0.co;2-3.
Previous Commission on Cancer Data from the National Cancer Data Base (NCDB) have examined time trends in stage of disease, treatment patterns, and survival for selected cancers. The most current (1993) data relating to patients with bladder carcinoma are described here.
Five calls for data have yielded a total of 3,700,000 cases for the years 1985 through 1993, including 447,679 cases for 1988 and 608,593 cases for 1993, from hospital cancer registries across the U.S. Data were received on 18,053 bladder carcinoma cases in 1988 and 22,606 cases in 1993.
Interesting trends are 1) younger patients (49 years of age and younger) present with earlier stages of disease than do older patients; 2) women are slightly more likely to be diagnosed with later stages (II, III, and IV) of bladder carcinoma than men; 3) African Americans are less likely to be diagnosed with Stage 0 or Stage I disease than either Hispanic or non-Hispanic whites; and 4) National Cancer Institute designated centers treat more patients with advanced disease than do other types of hospitals.
The NCDB data are important for analyzing what cancer treatments and outcomes are used and occurring in the country. The data suggest that African Americans are diagnosed at later stages of disease progression. The relative survival rates among African Americans are lower than among Hispanics or non-Hispanic whites. Also, the decreasing utility of adjuvant chemotherapy is being recognized.
国家癌症数据库(NCDB)先前的癌症委员会数据研究了特定癌症在疾病分期、治疗模式和生存率方面的时间趋势。此处描述了与膀胱癌患者相关的最新(1993年)数据。
五次数据征集共获得了1985年至1993年期间的370万例病例,其中1988年有447,679例,1993年有608,593例,数据来自美国各地的医院癌症登记处。1988年收到了18,053例膀胱癌病例的数据,1993年收到了22,606例病例的数据。
有趣的趋势有:1)年轻患者(49岁及以下)比老年患者疾病分期更早;2)女性比男性更有可能被诊断为膀胱癌的晚期(II、III和IV期);3)非裔美国人被诊断为0期或I期疾病的可能性低于西班牙裔或非西班牙裔白人;4)国家癌症研究所指定的中心比其他类型的医院治疗更多的晚期疾病患者。
NCDB数据对于分析该国使用的癌症治疗方法和治疗结果非常重要。数据表明非裔美国人在疾病进展的较晚期被诊断出来。非裔美国人的相对生存率低于西班牙裔或非西班牙裔白人。此外,辅助化疗的效用正在降低这一点也得到了认可。