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[肾细胞癌肝损害的诊断问题(施陶费尔综合征)]

[The problem of hepatic dysfunction of the diagnosis of hypernephroid kidney carcinomas (Stauffer syndrome)].

作者信息

Bischoff W

出版信息

Fortschr Med. 1979 Jun 28;97(24):1132-6.

PMID:88402
Abstract

In 43 patients with histologically proved hypernephroid kidney cancer evaluation of the electrophoretic results, serum alkaline phosphatase, thromboplastin time (Quick's time) and bromthalein retention (n = 10) was carried out. As a control group the serum values of 10 patients with clinical tentative diagnosis of hypernephroid kidney cancer were checked; in this group operation and histological examination showed no kidney tumor. Only in one patient we found the typical constellation with elevated alkaline phosphatase, diminished albumin, elevated alpha-2 globuline fraction, and decreased thromboplastin time. 10 patients with histologically proved hypernephroid kidney cancer (nephrectomy) did not show any hepatic dysfunctions. Concerning the laboratory findings there was no difference between the two groups. In case of hepatic dysfunctions of unknown etiology a liver punction should be carried out for histologically examination. The cause of hepatic dysfunction (Stauffer syndrome) in cases of hypernephroid kidney cancer are discussed.

摘要

对43例经组织学证实为肾上腺样肾癌的患者进行了电泳结果、血清碱性磷酸酶、凝血酶原时间(奎克氏时间)和酚四溴酞钠潴留(n = 10)的评估。作为对照组,检查了10例临床初步诊断为肾上腺样肾癌患者的血清值;该组患者经手术及组织学检查未发现肾肿瘤。仅在1例患者中发现了典型的组合,即碱性磷酸酶升高、白蛋白降低、α-2球蛋白组分升高以及凝血酶原时间缩短。10例经组织学证实为肾上腺样肾癌(肾切除术)的患者未表现出任何肝功能障碍。关于实验室检查结果,两组之间无差异。对于病因不明的肝功能障碍,应进行肝穿刺以进行组织学检查。文中讨论了肾上腺样肾癌病例中肝功能障碍(斯陶弗综合征)的病因。

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