Gurewitsch E D, Smith-Levitin M, Mack J
Department of Obstetrics and Gynecology, New York Hospital-Cornell Medical Center, New York, USA.
Obstet Gynecol. 1996 Oct;88(4 Pt 2):658-61. doi: 10.1016/0029-7844(96)00187-1.
Surgical treatment for severe obesity is sometimes recommended. Many long-term risks, particularly to adolescents and to subsequent pregnancies, are still being determined.
A 23-year-old woman, gravida 6, para 2, treated for morbid obesity during adolescence with gastric bypass surgery, presented at 6 weeks' gestation with severe microcytic anemia. Significant iron and cobalamin deficiencies were found. Although the vitamin B12 deficiency responded to parenteral treatment, the iron deficiency was refractory to oral supplementation because of malabsorption. By 30 weeks' gestation, the patient required blood transfusions to correct the progressive anemia. Subsequently, she delivered a healthy male infant at term.
Severe iron deficiency anemia resulting from malabsorption can complicate pregnancy following gastric bypass surgery for morbid obesity. For women of childbearing age, this potential adverse effect must be considered.
有时会推荐对重度肥胖进行手术治疗。许多长期风险,尤其是对青少年以及对后续妊娠的风险,仍在研究中。
一名23岁女性,孕6产2,青春期因病态肥胖接受胃旁路手术治疗,妊娠6周时出现严重小细胞贫血。发现有明显的铁和钴胺素缺乏。尽管维生素B12缺乏对肠外治疗有反应,但由于吸收不良,缺铁对口服补充剂无效。到妊娠30周时,患者需要输血来纠正进行性贫血。随后,她足月产下一名健康男婴。
胃旁路手术治疗病态肥胖后,吸收不良导致的严重缺铁性贫血会使妊娠复杂化。对于育龄妇女,必须考虑这种潜在的不良反应。