Roll C, Schmid E N, Menken U, Hanssler L
Department of Pediatrics, University of Essen, Germany.
Obstet Gynecol. 1996 Oct;88(4 Pt 2):692-3. doi: 10.1016/0029-7844(96)00076-2.
Before the advent of antibiotic therapy, Salmonella typhi infection during pregnancy was associated with a high incidence of fetal and neonatal death. Little information is available about the risk to the fetus or the newborn of a pregnant woman infected by non-typhoid salmonella, and treatment recommendations do not exist.
We report a case of transplacental infection of a fetus by non-typhoid salmonella in a woman with gastroenteritis. Salmonella enteritidis was cultured from stool of the pregnant woman, who had diarrhea and fever before cesarean was performed at 29 weeks' gestation. The premature girl died 4 hours after birth from septic shock. Salmonella enteritidis was cultured from blood cultures and swabs of the premature infant and from the placenta and uterus.
This observation argues in favor of antibiotic treatment for non-typhoid salmonella infection in pregnancy because of the risk of transplacental infection of the fetus.
在抗生素疗法出现之前，孕期感染伤寒沙门氏菌与胎儿及新生儿的高死亡率相关。关于非伤寒沙门氏菌感染孕妇时对胎儿或新生儿的风险，所知甚少，且不存在治疗建议。
我们报告一例患有肠胃炎的女性胎儿经胎盘感染非伤寒沙门氏菌的病例。从该孕妇的粪便中培养出肠炎沙门氏菌，该孕妇在妊娠29周行剖宫产术前出现腹泻和发热。早产女婴出生后4小时死于感染性休克。从早产婴儿的血培养物和拭子以及胎盘和子宫中培养出肠炎沙门氏菌。
这一观察结果支持对孕期非伤寒沙门氏菌感染进行抗生素治疗，因为存在胎儿经胎盘感染的风险。
