8-Methylguanine-containing oligonucleotides: useful structural constraint for Z form DNA.
作者信息
Kawai K, Sugiyama H, Fujimoto K, Saito I
机构信息
Department of Synthetic Chemistry and Biological Chemistry, Faculty of Engineering, Kyoto University, Japan.
出版信息
Nucleic Acids Symp Ser. 1995(34):33-4.
PMID:8841538
Abstract
The preparation and thermodynamic property of 8-methylguanine (8mG)-containing oligonucleotides were described. It was found that the introduction of a methyl group at the guanine C8 position remarkably stabilizes the Z conformation of short oligonucleotides of a variety of base sequences under low salt conditions.
摘要
Zotero 插件