在2'-糖基位置含有蒽醌的寡核苷酸与互补核酸的相互作用。
Interaction of oligonucleotides containing anthraquinone at the 2'-sugar position with complementary nucleic acids.
作者信息
Mitsui T, Yoshioka J, Isuno T, Yamana K, Nakano H
机构信息
Department of Applied Chemistry, Himeji Institute of Technology, Himeji, Japan.
出版信息
Nucleic Acids Symp Ser. 1995(34):35-6.
PMID:8841539
Abstract
Oligonucleotide 15-mers containing 2-anthraquinonylmethyl substituents at the different 2'-sugar residues have been synthesized. These oligomers exhibit increased stability in formation of hybrids with complementary DNA and RNA without loss of sequence specificity.
摘要
已合成了在不同2'-糖残基处含有2-蒽醌基甲基取代基的15聚体寡核苷酸。这些寡聚物在与互补DNA和RNA形成杂交体时表现出更高的稳定性，且不丧失序列特异性。
相似文献
1
Interaction of oligonucleotides containing anthraquinone at the 2'-sugar position with complementary nucleic acids.在2'-糖基位置含有蒽醌的寡核苷酸与互补核酸的相互作用。
Nucleic Acids Symp Ser. 1995(34):35-6.
2
Incorporation of two anthraquinonylmethyl groups into the 2'-O-positions of oligonucleotides: increased affinity and sequence specificity of anthraquinone-modified oligonucleotides in hybrid formation with DNA and RNA.将两个蒽醌甲基基团引入寡核苷酸的2'-O-位：蒽醌修饰的寡核苷酸在与DNA和RNA杂交形成中的亲和力和序列特异性增加。
Bioconjug Chem. 1996 Nov-Dec;7(6):715-20. doi: 10.1021/bc960064s.
3
Synthesis and interactive properties of an oligonucleotide with anthraquinone at the sugar fragment.
Bioconjug Chem. 1990 Sep-Oct;1(5):319-24. doi: 10.1021/bc00005a004.
4
Alpha-oligonucleotides: a unique class of modified chimeric nucleic acids.
Anticancer Drug Des. 1991 Dec;6(6):521-9.
5
Homo-N-oligonucleotides (N1/N9-C1' methylene bridge oligonucleotides): nucleic acids with left-handed helicity.同型-N-寡核苷酸（N1/N9-C1'亚甲基桥寡核苷酸）：具有左手螺旋结构的核酸。
J Am Chem Soc. 2004 Jun 23;126(24):7476-85. doi: 10.1021/ja049865t.
6
Mixed-sequence pyrrolidine-amide oligonucleotide mimics: Boc(Z) synthesis and DNA/RNA binding properties.混合序列吡咯烷-酰胺寡核苷酸模拟物：Boc(Z)合成及DNA/RNA结合特性
Org Biomol Chem. 2007 Jan 21;5(2):249-59. doi: 10.1039/b613386j. Epub 2006 Dec 1.
7
Synthesis and thermal denaturation studies of novel 2'-O,3'-C-linked bicyclic oligonucleotides with a methoxy or a piperazino group facing the major groove of nucleic acid duplexes.新型2'-O,3'-C-连接的双环寡核苷酸的合成及热变性研究，其甲氧基或哌嗪基朝向核酸双链体的大沟。
Org Biomol Chem. 2005 Jan 7;3(1):130-5. doi: 10.1039/b414454f. Epub 2004 Nov 18.
8
Stabilizing effect of propionic acid derivative of anthraquinone--polyamine conjugate incorporated into α-β chimeric oligonucleotides on the alternate-stranded triple helix.蒽醌-多胺偶联物的丙酸衍生物对α-β嵌合寡核苷酸中交替链三螺旋的稳定作用。
Bioconjug Chem. 2011 Jun 15;22(6):1039-45. doi: 10.1021/bc100446w. Epub 2011 May 25.
9
Synthesis and hybridization property of a boat-shaped pyranosyl nucleic acid containing an exocyclic methylene group in the sugar moiety.
Bioorg Med Chem. 2015 Jan 1;23(1):33-7. doi: 10.1016/j.bmc.2014.11.030. Epub 2014 Nov 28.
10
Nucleic acid binding properties of thyminyl and adeninyl pyrrolidine-amide oligonucleotide mimics (POM).胸腺嘧啶基和腺嘌呤基吡咯烷酰胺寡核苷酸模拟物（POM）的核酸结合特性
Chem Commun (Camb). 2004 Mar 7(5):516-7. doi: 10.1039/b315768g. Epub 2004 Jan 28.
Zotero 插件