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Gene therapy of malignant glioma via inhibition of tumor angiogenesis.

作者信息

Plate K H

机构信息

Department of Neuropathology, University of Freiburg Medical School, Germany.

出版信息

Cancer Metastasis Rev. 1996 Jun;15(2):237-40. doi: 10.1007/BF00437477.

DOI:10.1007/BF00437477
PMID:8842496
Abstract
摘要

相似文献

1
Gene therapy of malignant glioma via inhibition of tumor angiogenesis.通过抑制肿瘤血管生成对恶性胶质瘤进行基因治疗。
Cancer Metastasis Rev. 1996 Jun;15(2):237-40. doi: 10.1007/BF00437477.
2
[Topics for antiangiogenic therapy for glioblastoma].[胶质母细胞瘤抗血管生成治疗的主题]
No Shinkei Geka. 2012 Jun;40(6):481-502.
3
Anti-angiogenic gene therapy of malignant glioma.恶性胶质瘤的抗血管生成基因治疗
Acta Neurochir Suppl. 1997;68:105-10. doi: 10.1007/978-3-7091-6513-3_20.
4
Anti-angiogenic gene therapy in the treatment of malignant gliomas.抗血管生成基因治疗恶性脑胶质瘤。
Neurosci Lett. 2012 Oct 11;527(2):62-70. doi: 10.1016/j.neulet.2012.08.001. Epub 2012 Aug 10.
5
Antiangiogenic activity of BAI1 in vivo: implications for gene therapy of human glioblastomas.BAI1在体内的抗血管生成活性：对人类胶质母细胞瘤基因治疗的意义。
Cancer Gene Ther. 2006 Apr;13(4):385-92. doi: 10.1038/sj.cgt.7700898.
6
Immune responses in glioblastoma: an avenue to effective cancer therapy or a mere epiphenomenon?
Curr Top Microbiol Immunol. 2002;265:259-67. doi: 10.1007/978-3-662-09525-6_13.
7
EGFR and EGFRvIII Promote Angiogenesis and Cell Invasion in Glioblastoma: Combination Therapies for an Effective Treatment.表皮生长因子受体（EGFR）和截短型表皮生长因子受体变异体III（EGFRvIII）促进胶质母细胞瘤血管生成和细胞侵袭：有效治疗的联合疗法
Int J Mol Sci. 2017 Jun 18;18(6):1295. doi: 10.3390/ijms18061295.
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A plasmid-encoded VEGF siRNA reduces glioblastoma angiogenesis and its combination with interleukin-4 blocks tumor growth in a xenograft mouse model.
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Viral vector-targeted antiangiogenic gene therapy utilizing an angiostatin complementary DNA.利用血管抑素互补脱氧核糖核酸的病毒载体靶向抗血管生成基因疗法。
Cancer Res. 1998 Aug 1;58(15):3362-9.
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Taming glioblastoma by targeting angiogenesis: 3 years later.靶向血管生成治疗胶质母细胞瘤：三年之后
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Regulation of the hypoxic tumor environment in hepatocellular carcinoma using RNA interference.利用RNA干扰调控肝细胞癌中的缺氧肿瘤环境
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2
The immunopharmacologic potential of Semaxanib and new generation directed therapeutic drugs: Receptor tyrosine kinase regulation with anti-tumorigenensis/angiogenesis properties.西马替尼和新一代靶向治疗药物的免疫药理学潜力：具有抗肿瘤/血管生成特性的受体酪氨酸激酶调节。
Saudi Pharm J. 2012 Apr;20(2):103-23. doi: 10.1016/j.jsps.2011.09.002. Epub 2011 Sep 23.
3
Inhibitory effect of antisense vascular endothelial growth factor 165 eukaryotic expression vector on proliferation of hepatocellular carcinoma cells.

本文引用的文献

1
Angiogenesis in malignant gliomas.恶性胶质瘤中的血管生成
Glia. 1995 Nov;15(3):339-47. doi: 10.1002/glia.440150313.
2
Glioblastoma growth inhibited in vivo by a dominant-negative Flk-1 mutant.一种显性负性Flk-1突变体在体内抑制胶质母细胞瘤生长。
Nature. 1994 Feb 10;367(6463):576-9. doi: 10.1038/367576a0.
3
Up-regulation of vascular endothelial growth factor and its cognate receptors in a rat glioma model of tumor angiogenesis.大鼠肿瘤血管生成性胶质瘤模型中血管内皮生长因子及其同源受体的上调
反义血管内皮生长因子165真核表达载体对肝癌细胞增殖的抑制作用
World J Gastroenterol. 2004 Feb 15;10(4):535-9. doi: 10.3748/wjg.v10.i4.535.
4
Vascular patterns in glioblastoma influence clinical outcome and associate with variable expression of angiogenic proteins: evidence for distinct angiogenic subtypes.胶质母细胞瘤中的血管模式影响临床结果并与血管生成蛋白的可变表达相关：不同血管生成亚型的证据。
Brain Pathol. 2003 Apr;13(2):133-43. doi: 10.1111/j.1750-3639.2003.tb00013.x.
Cancer Res. 1993 Dec 1;53(23):5822-7.
4
Vascular endothelial growth factor receptor expression during embryogenesis and tissue repair suggests a role in endothelial differentiation and blood vessel growth.血管内皮生长因子受体在胚胎发生和组织修复过程中的表达表明其在内皮细胞分化和血管生长中发挥作用。
Proc Natl Acad Sci U S A. 1993 Oct 1;90(19):8915-9. doi: 10.1073/pnas.90.19.8915.
5
Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo.抑制血管内皮生长因子诱导的血管生成可在体内抑制肿瘤生长。
Nature. 1993 Apr 29;362(6423):841-4. doi: 10.1038/362841a0.
6
High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis.高亲和力的血管内皮生长因子结合及发育表达表明Flk-1是血管发生和血管生成的主要调节因子。
Cell. 1993 Mar 26;72(6):835-46. doi: 10.1016/0092-8674(93)90573-9.
7
Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium.Flt-1受体酪氨酸激酶在调节血管内皮组装中的作用。
Nature. 1995 Jul 6;376(6535):66-70. doi: 10.1038/376066a0.
8
Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice.Flk-1基因缺陷小鼠中血岛形成和血管发生的失败。
Nature. 1995 Jul 6;376(6535):62-6. doi: 10.1038/376062a0.
9
Hypoxia-induced transcriptional activation and increased mRNA stability of vascular endothelial growth factor in C6 glioma cells.缺氧诱导C6胶质瘤细胞中血管内皮生长因子的转录激活及mRNA稳定性增加。
J Biol Chem. 1995 Aug 25;270(34):19761-6. doi: 10.1074/jbc.270.34.19761.
10
Vascular endothelial growth factor and glioma angiogenesis: coordinate induction of VEGF receptors, distribution of VEGF protein and possible in vivo regulatory mechanisms.血管内皮生长因子与胶质瘤血管生成：VEGF受体的协同诱导、VEGF蛋白的分布及可能的体内调节机制
Int J Cancer. 1994 Nov 15;59(4):520-9. doi: 10.1002/ijc.2910590415.