Akins C W
Cardiac Surgical Unit, Massachusetts General Hospital, Boston, USA.
Semin Thorac Cardiovasc Surg. 1996 Jul;8(3):242-8.
The unique design of the Medtronic-Hall single-tilting disc aortic valvular prosthesis includes a wider opening angle and larger lesser orifice for its pyrolytic carbon disc, translation of the disc downstream in systole, machining of the support struts and the central post from one piece of titanium, and a sewing ring made of knitted polytetrafluoroethylene fabric. These design features have achieved the goals of unsurpassed durability, excellent hemodynamic function, and acceptably low rates of valve-related complications. Gradient relief, even in the smaller sizes, is as good as any other mechanical valve. There has never been a report of clinical loss of structural integrity of a Medtronic-Hall aortic valve. The composite linearized rates (% per patient-year) from the global literature for valve-related complications are as follows: nonstructural dysfunction, 0.5; thromboembolism, 1.4; thrombosis, 0.2; anticoagulant-related bleeding, 0.9; and prosthetic endocarditis, 0.5. The Medtronic-Hall aortic prosthesis is an excellent choice for mechanical replacement of the aortic valve.
美敦力-霍尔单倾斜盘式主动脉瓣膜假体的独特设计包括：其热解碳盘具有更宽的开口角度和更大的较小孔口，盘在收缩期向下游平移，支撑支柱和中心柱由一块钛加工而成，以及由针织聚四氟乙烯织物制成的缝合环。这些设计特点实现了无与伦比的耐用性、出色的血液动力学功能以及瓣膜相关并发症发生率低至可接受水平的目标。即使在较小尺寸下，压力阶差缓解效果也与任何其他机械瓣膜一样好。从未有过美敦力-霍尔主动脉瓣膜结构完整性临床丧失的报告。来自全球文献的瓣膜相关并发症的复合线性化发生率（每年每位患者的百分比）如下：非结构性功能障碍为0.5；血栓栓塞为1.4；血栓形成，0.2；抗凝相关出血，0.9；以及人工瓣膜心内膜炎，0.5。美敦力-霍尔主动脉假体是主动脉瓣机械置换的绝佳选择。
