Howard A N, Williams N R, Palmer C R, Cambou J P, Evans A E, Foote J W, Marques-Vidal P, McCrum E E, Ruidavets J B, Nigdikar S V, Rajput-Williams J, Thurnham D I
Department of Pathology, Papworth Hospital NHS Trust, Cambridge, UK.
Int J Vitam Nutr Res. 1996;66(2):113-8.
High intakes of antioxidants in fruit, vegetables and wine are thought to protect against coronary heart disease (CHD). Because people in Toulouse have a much lower incidence of CHD compared with Belfast, the plasma concentrations of antioxidant vitamins and carotenoids in the two populations have been compared. The major difference was in some of the plasma carotenoids. Hydroxy-carotenoids were twice as high in Toulouse in both sexes, notably lutein which occurs principally in dark green vegetables and beta-cryptoxanthin which occurs chiefly in citrus fruits. In addition, alpha-carotene was 50% higher in Toulouse, gamma-tocopherol was 50% higher in Belfast. Other plasma vitamins and carotenoids were not significantly different. If antioxidants play a role in preventing CHD, then the hydroxy-carotenoids are major candidates for further investigation.
水果、蔬菜和葡萄酒中高含量的抗氧化剂被认为可以预防冠心病（CHD）。由于图卢兹的居民患冠心病的几率比贝尔法斯特低得多，因此对这两个人群的抗氧化维生素和类胡萝卜素的血浆浓度进行了比较。主要差异在于某些血浆类胡萝卜素。羟基类胡萝卜素在图卢兹的两性中都高出两倍，特别是叶黄素（主要存在于深绿色蔬菜中）和β-隐黄质（主要存在于柑橘类水果中）。此外，α-胡萝卜素在图卢兹高出50%，γ-生育酚在贝尔法斯特高出50%。其他血浆维生素和类胡萝卜素没有显著差异。如果抗氧化剂在预防冠心病中起作用，那么羟基类胡萝卜素是进一步研究的主要候选对象。
