Khvoles R, Freeman S, Sohmer H
Center of Audiology and Hearing Rehabilitation, Tbilisi, Georgia.
Hear Res. 1996 Aug;97(1-2):120-6.
Transient (click) evoked (TEOAE) and distortion product (DPOAE) otoacoustic emissions can be recorded in most normal human ears. Even though DPOAEs have been recorded in many laboratory animals, there has not been much success in recording TEOAEs in non-primate mammals except for guinea pigs. In this study, TEOAEs were unequivocally recorded in every rat (and guinea pig) ear studied by using short pulses (40 microseconds) to generate the clicks and a short (1.1 ms) amplifier gain suppression period. The responses were reproducible in the same rat, above the noise floor and disappeared post-mortem. They were shorter in duration in rats than in guinea pigs and were made up of a broadband frequency spectrum between 2 and 4 kHz. Post-mortem, the TEOAEs to 65 dB SPL clicks disappeared at about the same time as DPOAEs to low stimulus intensities and before the DPOAEs to high stimulus intensities. The ability to record TEOAEs in rats and other animals should permit further experimentation into the basic mechanisms of generation of otoacoustic emissions in general and TEOAEs in particular.
瞬态（点击）诱发耳声发射（TEOAE）和畸变产物耳声发射（DPOAE）在大多数正常人类耳朵中都可记录到。尽管已在许多实验动物中记录到DPOAE，但除豚鼠外，在非灵长类哺乳动物中记录TEOAE并未取得太大成功。在本研究中，通过使用短脉冲（40微秒）产生点击声以及短（1.1毫秒）的放大器增益抑制期，在每只被研究的大鼠（和豚鼠）耳朵中都明确记录到了TEOAE。这些反应在同一只大鼠中具有可重复性，高于本底噪声，且在死后消失。它们在大鼠中的持续时间比豚鼠短，由2至4千赫兹的宽带频谱组成。死后，65分贝声压级点击声诱发的TEOAE与低刺激强度下的DPOAE大约在同一时间消失，且早于高刺激强度下的DPOAE。在大鼠和其他动物中记录TEOAE的能力应能允许对耳声发射产生的基本机制，尤其是TEOAE产生的基本机制进行进一步实验。
