Whipple D L, Bolin C A, Miller J M
Zoonotic Diseases Research Unit, USDA, Ames, IA 50010, USA.
J Vet Diagn Invest. 1996 Jul;8(3):351-4. doi: 10.1177/104063879600800312.
Detailed postmortem examinations were conducted on 30 cattle from a dairy herd with bovine tuberculosis to determine the distribution of lesions in Mycobacterium bovis-infected cattle. Twenty-four different tissue specimens from each animal were examined for gross lesions and collected for bacteriologic culturing and histologic examination. Tuberculosis was confirmed in 15 cattle with evidence of infection in 1 or more of the following tissues: medial retropharyngeal, parotid, tracheobronchial, mediastinal, caudal deep cervical, and subiliac lymph nodes; palatine tonsil; and lung. Gross and histologic lesions were present most frequently in lymph nodes of the thoracic region. Mycobacterium bovis was isolated from 3 cattle that had no gross lesions of tuberculosis. One animal had lesions only in the subiliac lymph node, which is not routinely examined during slaughter surveillance. Results of this study indicate that not all cattle infected with M. bovis have visible lesions of tuberculosis in sites that are routinely inspected. These findings are important because detection of gross lesions of tuberculosis during inspection of carcasses at slaughter is the primary method for detection of tuberculous cattle and herds in the United States.
对来自一个患有牛结核病的奶牛群的30头牛进行了详细的尸检，以确定牛分枝杆菌感染牛的病变分布。对每头牛的24种不同组织标本进行大体病变检查，并采集用于细菌培养和组织学检查。在15头牛中确诊患有结核病，感染证据存在于以下1个或多个组织中：咽后内侧、腮腺、气管支气管、纵隔、颈深尾侧和髂下淋巴结；腭扁桃体；以及肺。大体和组织学病变最常出现在胸部区域的淋巴结中。从3头没有结核病大体病变的牛中分离出了牛分枝杆菌。有1头牛仅在髂下淋巴结有病变，而在屠宰监测期间通常不会检查该淋巴结。本研究结果表明，并非所有感染牛分枝杆菌的牛在常规检查部位都有可见的结核病变。这些发现很重要，因为在屠宰时检查胴体的结核大体病变是美国检测患结核病的牛和牛群的主要方法。
