Sullivan T J, Clarke M P, Tuli R, Devenyi R, Harvey P
Department of Ophthalmology, Hospital for Sick Children, Toronto, Ontario, Canada.
Eur J Ophthalmol. 1995 Jul-Sep;5(3):187-91. doi: 10.1177/112067219500500308.
We present a technique for treating retinopathy of prematurity (ROP) with cryotherapy under general anesthesia, administered and monitored by a neonatologist, with endotracheal intubation in the neonatal intensive care unit that avoids the serious systemic complications associated with the administration of local anesthetics. Although no significant complications arose in this series, having the intubated infant monitored by trained neonatology staff allows appropriate management should complications arise. We have used this technique to treat 20 eyes with threshold ROP. The mean time to extubation was 40.2 hours. The systemic status and discharge from the neonatal intensive care unit were not influenced by the general anesthesia. This technique allows quick and accurate application of the cryotherapy in a stable and controlled setting. We recommend that physicians consider cryotherapy under general anesthesia with endotracheal intubation for infants with ROP. This technique allows ROP to be treated adequately with minimal risk to the infant.
我们介绍了一种在全身麻醉下用冷冻疗法治疗早产儿视网膜病变（ROP）的技术，该技术由新生儿科医生实施和监测，在新生儿重症监护病房进行气管插管，避免了与局部麻醉剂给药相关的严重全身并发症。尽管在该系列中未出现重大并发症，但让插管婴儿由训练有素的新生儿科工作人员进行监测，以便在出现并发症时能进行适当处理。我们已使用该技术治疗了20只患有阈值ROP的眼睛。拔管的平均时间为40.2小时。全身状况和从新生儿重症监护病房出院不受全身麻醉的影响。该技术允许在稳定且可控的环境中快速准确地应用冷冻疗法。我们建议医生考虑对患有ROP的婴儿采用气管插管全身麻醉下的冷冻疗法。该技术能以对婴儿最小的风险充分治疗ROP。
