Pozzi D, Vázquez S, Petracchi M, Dancygier G, García H, Starkstein S
Department of Neuropsychiatry, Raúl Carrea Institute of Neurological Research, Buenos Aires, Argentina.
J Neuropsychiatry Clin Neurosci. 1996 Winter;8(1):26-32. doi: 10.1176/jnp.8.1.26.
The authors examined the presence of specific quantified electroencephalographic (qEEG) changes in dementia patients with relatively lower frontal or parietal blood perfusion as demonstrated by SPECT. Over all brain regions, patients with relatively lower parietal perfusion showed significantly higher theta relative power than demented patients with relatively lower frontal perfusion or normal control subjects. Dementia patients with relatively lower frontal perfusion showed no differences from age-comparable normal control subjects in qEEG variables. These findings 1) suggest that usefulness of qEEG for the diagnosis of dementia is restricted to a subgroup of patients with the typical SPECT pattern of parietal blood hypoperfusion and 2) demonstrate that the qEEG changes typical of dementia are not related to perfusion deficits in frontal brain areas.
作者们研究了单光子发射计算机断层扫描（SPECT）显示额叶或顶叶血流灌注相对较低的痴呆患者中特定定量脑电图（qEEG）变化的存在情况。在所有脑区中，顶叶灌注相对较低的患者与额叶灌注相对较低的痴呆患者或正常对照受试者相比，其θ相对功率显著更高。额叶灌注相对较低的痴呆患者在qEEG变量方面与年龄相仿的正常对照受试者没有差异。这些发现1）表明qEEG对痴呆诊断的有用性仅限于具有典型顶叶血流灌注不足SPECT模式的患者亚组，并且2）证明痴呆典型的qEEG变化与额叶脑区的灌注不足无关。
