Schoevaerdts J C
Bull Mem Acad R Med Belg. 1995;150(10-11):430-8; discussion 438-41.
161 patients underwent an aortic valve replacement from 1966 till January 1995 for active infective endocarditIS of the native aortic valve. The disease extended to the other cardiac valves in 39 patients and to the surrounding areas in 42 (aortic root and subaortic myocardial tissues). Indications for surgery were: congestive heart failure in 123, uncontrolled sepsis in 44 and emboli in 24. Total follow-up was 1,120 patient-years with a maximum follow-up of 29 years. Early mortality was 8%; late mortality was 3.6%/patient-year; recurrence rate of endocarditis was 1.3%/patient year; survival and reoperation free curve was 68% (S.E. +/- 0.04) at 10 years. These long term results are in favour of a surgical attitude with an acceptable surgical risk without delay.
1966年至1995年1月期间，161例患者因原发性主动脉瓣活动性感染性心内膜炎接受了主动脉瓣置换术。39例患者的疾病蔓延至其他心脏瓣膜，42例（主动脉根部和主动脉下心肌组织）蔓延至周围区域。手术指征为：123例充血性心力衰竭，44例败血症控制不佳，24例发生栓塞。总随访时间为1120患者年，最长随访时间为29年。早期死亡率为8%；晚期死亡率为3.6%/患者年；心内膜炎复发率为1.3%/患者年；10年时无生存和再次手术的曲线为68%（标准误±0.04）。这些长期结果支持在手术风险可接受的情况下毫不延迟地采取手术治疗态度。
