Cormio L, Edgren J, Lepäntalo M, Lindfors O, Nisén H, Saarinen O, Ruutu M
Department of Urology, School of Medicine, University of Bari, Italy.
Eur J Vasc Endovasc Surg. 1996 May;11(4):453-7. doi: 10.1016/s1078-5884(96)80181-x.
To determine the incidence and pathophysiology of erectile dysfunction (ED) in patients with aortoiliac occlusive disease (AIOD) and the effects of aortofemoral surgery, including endarterectomy (E) and reconstruction (R), on erectile function (EF).
Evaluation of EF before and 3 months after surgery.
31 out of 40 male patients scheduled for aortofemoral surgery were given multiple choice questionnaires and penile dynamic Colour Doppler Ultrasonography.
Of the 31 who agreed to enter the study five (16%) were found to be potent and 26 (84%) to suffer from ED. This was purely arteriogenic in 8% of the cases, purely venogenic in 23%, combined arteriogenic and venogenic in 53%, and neurogenic in 16%. Twenty patients returned for postoperative evaluation of EF, nine who had undergone E and 11 who had undergone R. Improvement of EF, in terms of increased penile arterial inflow, occurred in seven patients, six who had undergone E and one who had undergone R. EF remained unchanged in nine patients, three who had undergone E and six who had undergone R. Deterioration of EF occurred in four patients, all who had undergone R, and was attributable to decreased arterial inflow in two cases and to neurogenic surgical injury in the other two.
The majority of patients with AIOD suffers from ED. Reduced penile arterial inflow and cavernovenous leakage are equally important in the pathophysiology of ED in patients with AIOD, suggesting that atherosclerosis may also compromise the penile veno-occlusive mechanism. Endarterectomy seems more likely than reconstruction to improve or maintain EF.
确定主髂动脉闭塞性疾病(AIOD)患者勃起功能障碍(ED)的发生率和病理生理学,以及主股动脉手术,包括动脉内膜切除术(E)和重建术(R)对勃起功能(EF)的影响。
评估手术前和手术后3个月的EF。
40例计划进行主股动脉手术的男性患者中有31例接受了多项选择题问卷调查和阴茎动态彩色多普勒超声检查。
在同意参加研究的31例患者中,发现5例(16%)勃起功能正常,26例(84%)患有ED。其中,单纯动脉源性的占8%,单纯静脉源性的占23%,动静脉混合性的占53%,神经源性的占16%。20例患者返回进行术后EF评估,9例接受了E手术,11例接受了R手术。7例患者的EF有所改善,表现为阴茎动脉血流增加,其中接受E手术的有6例,接受R手术的有1例。9例患者的EF保持不变(接受E手术的3例,接受R手术的6例)。4例患者的EF恶化,均接受了R手术,其中2例是由于动脉血流减少,另外2例是由于神经源性手术损伤。
大多数AIOD患者患有ED。阴茎动脉血流减少和海绵体静脉漏在AIOD患者ED的病理生理学中同样重要,这表明动脉粥样硬化可能也会损害阴茎静脉闭塞机制。动脉内膜切除术似乎比重建术更有可能改善或维持EF。