An optimized examination protocol for contrast-enhanced cervical and mediastinal CT.

We compared an optimized contrast-enhanced CT technique for the neck and upper mediastinum with a conventional technique and with nonenhanced images, using densitometric measurements. The optimized protocol included slice thickness, infusion rate, postural maneuvers, and manipulation of the gantry tilt. Densitometric evaluation showed significantly higher enhancement values in vessels and metastases with the optimized protocol than with conventional technique, without significant enhancement in muscle. Semiquantitative assessment demonstrated significantly better image quality with the optimized protocol. The optimized technique has been implemented into routine use.