Barinov E F, Ziablitsev S V
Fiziol Zh (1994). 1995 Jan-Apr;41(1-2):86-91.
Experiments on white male rats with a traumatic shock by the Cannon method have permitted establishing that expressed activation of hypothalamo-neurohypophysial, renin-angiotensin-aldosterone and prostanoid systems induced disorders in the cardiovascular system, namely, a decrease in the heart stroke, growth of the vascular tension in the first hours of the acute period of the disease and an increase in the peripheral vascular resistance. Besides, the renin plasma activity falls, which may be a sanogenesis mechanism preventing redundant stimulation of the vessels and myocardium.
采用坎农法对遭受创伤性休克的雄性白鼠进行的实验已证实，下丘脑 - 神经垂体、肾素 - 血管紧张素 - 醛固酮和前列腺素系统的明显激活会引发心血管系统紊乱，即心搏量减少、疾病急性期最初数小时血管张力增加以及外周血管阻力增大。此外，血浆肾素活性下降，这可能是一种机体自身保护机制，可防止血管和心肌受到过度刺激。
