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从血细胞入胞现象角度对血小板生成机制的评估

[The evaluation of the mechanism of thrombocytopoiesis from the viewpoint of the phenomenon of emperipolesis].

作者信息

Mikhaĭlovskaia E V

出版信息

Lik Sprava. 1995 Jul-Aug(7-8):146-51.

PMID:8846355
Abstract

Cytolytic aggressiveness of bone marrow leucocytes towards megakaryocytes was documented with the aid of a phase contrast Zeitraffer microfilming of alive cells technique. The difference was found between the process above and cell interaction through emperipolesis. The author comes to the conclusion that leucocytes play an active part in platelet production regulation. The data obtained enable new pathognomic methods of treatment to be developed and preventive measures to be devised against blood platelet cytosis involved in the morbid course of quite a number of medical conditions, and further studies to be made.

摘要

借助对活细胞进行相差快速摄影技术,记录了骨髓白细胞对巨核细胞的溶细胞侵袭性。发现上述过程与通过血细胞吞噬作用的细胞相互作用之间存在差异。作者得出结论,白细胞在血小板生成调节中起积极作用。所获得的数据有助于开发新的病理诊断治疗方法,制定针对许多疾病病程中涉及的血小板增多症的预防措施,并开展进一步研究。

相似文献

1
[The evaluation of the mechanism of thrombocytopoiesis from the viewpoint of the phenomenon of emperipolesis].从血细胞入胞现象角度对血小板生成机制的评估
Lik Sprava. 1995 Jul-Aug(7-8):146-51.
2
The influencing of thrombocytopoiesis with irradiation.辐射对血小板生成的影响。
Acta Univ Carol Med Monogr. 1987;119:23-33.
3
Postirradiation thrombocytopoiesis: suppression, recovery, compensatory states, and macromegakaryocytosis.辐照后血小板生成:抑制、恢复、代偿状态及巨核细胞增多症。
Prog Clin Biol Res. 1986;215:71-89.
4
[Capacity of bone marrow cells to restore thrombocytopoiesis in lethally irradiated animals].[骨髓细胞在致死性照射动物中恢复血小板生成的能力]
Tsitologiia. 1985 Aug;27(8):928-32.
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Bone marrow regeneration in germfree NO-2 mice after 700 rad whole body irradiation.无菌NO-2小鼠经700拉德全身照射后的骨髓再生
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Emperipolesis of marrow cells within megakaryocytes in the bone marrow of sublethally irradiated mice.亚致死剂量照射小鼠骨髓中巨核细胞内骨髓细胞的emperipolesis现象 。(注:emperipolesis这个词可能是医学术语,一般直接保留原文,此处按要求进行了翻译)
Ann Hematol. 1995 Feb;70(2):91-5. doi: 10.1007/BF01834387.
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Erythropoiesis, but not thrombocytopoiesis, is affected by the presence of a large amount of subcutaneously implanted bone marrow.大量皮下植入骨髓的存在会影响红细胞生成,但不影响血小板生成。
Exp Hematol. 1994 Sep;22(10):1011-5.
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Bone marrow megakaryocyte system and plasma thrombopoietic activity in x-ray irradiated mice with and without partial shielding.有或无部分屏蔽的X射线照射小鼠的骨髓巨核细胞系统及血浆血小板生成活性
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[The stimulation of postradiation thrombocytopoiesis by low-intensity laser radiation].[低强度激光辐射对辐射后血小板生成的刺激作用]
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[Patterns of thrombocytopoiesis regulation].[血小板生成调节模式]
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