门静脉高压症患者检查结果的血流动力学分析：日本多中心分析。日本门静脉高压症研究组

Hemodynamic analysis of findings in patients with portal hypertension: multicenter analysis in Japan. Japan Portal Hypertension Study Group.

作者信息

Aoki H, Hasumi A, Hashizume M, Kato H, Moriyasu F, Idezuki Y

机构信息

Department of Surgery, Fujita Health University.

出版信息

Hepatogastroenterology. 1995 Nov-Dec;42(6):1030-8.

PMID:8847016

Abstract

BACKGROUND/AIMS: A multicenter study was done to assess the pathophysiology of malcirculation with portal hypertension.

PATIENTS AND METHODS

Patients were admitted to 48 different institutes from 1990 to 1992.

RESULTS

Portal venous pressure was 345.9 +/- 72.1 mmH2O in patients with portal hypertension. In patients with liver cirrhosis, the diameter of the splenic artery, of the proper hepatic artery, of the left gastric artery and of the splenic vein was significantly larger (p<0.05) than seen in the controls without portal hypertension. In patients with idiopathic portal hypertension, the diameter of the splenic artery and of the vein was significantly larger (p<0.05) and that of the proper hepatic artery was significantly smaller (p<0.05) than seen in the cirrhotic patients. In the cirrhotic patients, blood flow volume was significantly larger (p<0.05) in the splenic vein. In patient with idiopathic portal hypertension, blood flow volume in the portal vein and splenic vein were significantly larger (p<0.05) and that of superior mesenteric vein showed an increasing tendency to enlarge.

CONCLUSION

This study shows that a hyperdynamic state is present in patient with portal hypertension.

摘要

背景/目的：开展一项多中心研究以评估门静脉高压时血液循环不良的病理生理学。

患者与方法

1990年至1992年期间，患者被收治于48个不同机构。

结果

门静脉高压患者的门静脉压力为345.9±72.1毫米水柱。肝硬化患者的脾动脉、肝固有动脉、胃左动脉及脾静脉直径显著大于（p<0.05）无门静脉高压的对照组。特发性门静脉高压患者的脾动脉和脾静脉直径显著大于（p<0.05）肝硬化患者，而肝固有动脉直径显著小于（p<0.05）肝硬化患者。肝硬化患者脾静脉的血流量显著更大（p<0.05）。特发性门静脉高压患者门静脉和脾静脉的血流量显著更大（p<0.05），肠系膜上静脉血流量有增大趋势。