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西班牙创伤重症监护病房(TICU)应用TRISS方法的流行病学特征及结果

Epidemiologic aspects and results of applying the TRISS methodology in a Spanish trauma intensive care unit (TICU).

作者信息

Suárez-Alvarez J R, Miquel J, Del Río F J, Ortega P

机构信息

Trauma Intensive Care Unit, Hospital Universitario San Carlos, Universidad Complutense, Madrid, Spain.

出版信息

Intensive Care Med. 1995 Sep;21(9):729-36. doi: 10.1007/BF01704740.

DOI:10.1007/BF01704740
PMID:8847428
Abstract

OBJECTIVE

Analysis of epidemiologic aspects in a trauma intensive care unit (TICU) and assessment of predicted outcomes.

DESIGN

Prospective study. Samples collected over a 2-year period.

SETTING

A Spanish TICU at a tertiary care centre.

PATIENTS

A group of 404 trauma patients.

INTERVENTIONS

TRISS methodology was applied.

MAIN RESULTS

Mean age was 35.8 +/- 17 years. Mortality was 19.6% over a median ISS = 17. Blunt trauma was more frequent than penetrating trauma (90.1% versus 9.9%). Car accident was the major aetiological factor (32.4%) and the highest mortality was among struck pedestrians (26.4%). The cranial region showed the highest incidence of lesion (57.9%) and the neurological complications on stage were the commonest reported on the discharge forms (49.7%). Mechanical ventilatory support (MVS) was applied in 53.2% of patients, with a relative mortality of 35.8%. Survivors differed significantly from nonsurvivors in terms of age, Glasgow Coma Scale rating, RTS, ISS, TRISS, stage and number of complications reported. The risk factors found to be associated with mortality were injury to cranial and abdominal/pelvic regions and age over 65. The TRISS total accuracy was 0.88 (sensitivity = 0.67; specificity = 0.93; area under the ROC curve = 0.85 +/- 0.03). Forward stepwise logistic regression analysis selected age, ISS and RTS as the best predictors of survival. When our TRISS results were compared with those anticipated on the basis the MTOS, an injury severity mismatch appeared (z = 0.02; M = 0.78).

CONCLUSIONS

We found a 19.6% mortality in the TICU. Cranial and abdominal/pelvic injury and age over 65 were the main risk factors on admittance. Clinically, we finally agreed with the majority of TRISS outcome predictions. However, we could not statistically validate the apparent clinical goodness of the TRISS methodology.

摘要

目的

分析创伤重症监护病房(TICU)的流行病学特征并评估预测结果。

设计

前瞻性研究。在2年期间收集样本。

地点

一家三级护理中心的西班牙TICU。

患者

一组404例创伤患者。

干预措施

应用TRISS方法。

主要结果

平均年龄为35.8±17岁。在中位损伤严重度评分(ISS)=17时,死亡率为19.6%。钝性创伤比穿透性创伤更常见(90.1%对9.9%)。车祸是主要病因(32.4%),死亡率最高的是被撞行人(26.4%)。颅脑区域损伤发生率最高(57.9%),出院表格中报告最多的阶段性神经并发症(49.7%)。53.2%的患者应用了机械通气支持(MVS),相对死亡率为35.8%。幸存者与非幸存者在年龄、格拉斯哥昏迷量表评分、创伤评分(RTS)、ISS、TRISS、阶段及报告的并发症数量方面存在显著差异。发现与死亡率相关的危险因素为颅脑和腹部/盆腔区域损伤以及年龄超过65岁。TRISS总准确率为0.88(敏感性=0.67;特异性=0.93;ROC曲线下面积=0.85±0.03)。向前逐步逻辑回归分析选择年龄、ISS和RTS作为生存的最佳预测因素。当将我们的TRISS结果与基于MTOS预期的结果进行比较时,出现了损伤严重度不匹配(z=0.02;M=0.78)。

结论

我们发现TICU的死亡率为19.6%。颅脑和腹部/盆腔损伤以及年龄超过65岁是入院时的主要危险因素。临床上,我们最终与大多数TRISS结果预测一致。然而,我们无法从统计学上验证TRISS方法明显的临床有效性。

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