Horn C C, Mitchell J C
Department of Psychology, Kansas State University, Manhattan 66506, USA.
Physiol Behav. 1996 Jan;59(1):33-8. doi: 10.1016/0031-9384(95)02020-9.
We investigated the effects of selective vagotomy on the learning of conditioned flavor preferences associated with intragastric Polycose infusion. Normal control, hepatic branch vagotomized, and gastric vagotomized rats implanted with gastric catheters received a flavor (CS+) paired with intragastric Polycose infusion, and on alternate days, a different flavor (CS-) paired with intragastric water infusion. After training, rats were given a two-bottle extinction test for 12 days. The results show that normal control and hepatic branch vagotomized rats had a significant CS+ flavor preference during extinction testing, whereas the gastric vagotomized rats showed no preference. This result indicates that the hepatic branch of the vagus does not play a solitary role in learned flavor-nutrient preferences using Polycose. However, the gastric vagal branches may be involved in the preference learning.
我们研究了选择性迷走神经切断术对与胃内灌注多糖相关的条件性味觉偏好学习的影响。植入胃导管的正常对照组、肝支迷走神经切断组和胃迷走神经切断组大鼠接受一种与胃内灌注多糖配对的味道（条件刺激+），并在隔天接受另一种与胃内灌注水配对的不同味道（条件刺激-）。训练后，大鼠进行为期12天的双瓶消退试验。结果显示，正常对照组和肝支迷走神经切断组大鼠在消退试验期间对条件刺激+味道有显著偏好，而胃迷走神经切断组大鼠则无偏好。这一结果表明，迷走神经的肝支在利用多糖进行的习得性味觉-营养偏好中并非起单独作用。然而，胃迷走神经分支可能参与了偏好学习。
