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核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Díaz Gil J, Rossi I, Escartín P, Segovia J M, Gosálvez M

Clin Sci Mol Med. 1977 Jun;52(6):599-606. doi: 10.1042/cs0520599.

Mitochondria and microsomal fractions have been isolated from liver biopsies from patients with alcoholic cirrhosis, cryptogenic cirrhosis or chronic aggressive hepatitis. 2. Cirrhotic livers yieled fewer mitochondria than normal liver. 3. The most significant change was a decrease in mitochondrial respiratory control. Cirrhotic microsomal fractions had a 50% diminution in cytochrome b5 and cytochrome P-450 content. 4. The two patients with chronic aggressive hepatitis showed similar mitochondrial and microsomal changes.

已从酒精性肝硬化、隐源性肝硬化或慢性侵袭性肝炎患者的肝活检组织中分离出线粒体和微粒体组分。2. 肝硬化肝脏产生的线粒体比正常肝脏少。3. 最显著的变化是线粒体呼吸控制的降低。肝硬化微粒体组分中的细胞色素b5和细胞色素P - 450含量减少了50%。4. 两名慢性侵袭性肝炎患者表现出相似的线粒体和微粒体变化。

Díaz Gil J, Rossi I, Escartín P, Segovia J M, Gosálvez M

Clin Sci Mol Med. 1977 Jun;52(6):599-606. doi: 10.1042/cs0520599.

Mitochondria and microsomal fractions have been isolated from liver biopsies from patients with alcoholic cirrhosis, cryptogenic cirrhosis or chronic aggressive hepatitis. 2. Cirrhotic livers yieled fewer mitochondria than normal liver. 3. The most significant change was a decrease in mitochondrial respiratory control. Cirrhotic microsomal fractions had a 50% diminution in cytochrome b5 and cytochrome P-450 content. 4. The two patients with chronic aggressive hepatitis showed similar mitochondrial and microsomal changes.

已从酒精性肝硬化、隐源性肝硬化或慢性侵袭性肝炎患者的肝活检组织中分离出线粒体和微粒体组分。2. 肝硬化肝脏产生的线粒体比正常肝脏少。3. 最显著的变化是线粒体呼吸控制的降低。肝硬化微粒体组分中的细胞色素b5和细胞色素P - 450含量减少了50%。4. 两名慢性侵袭性肝炎患者表现出相似的线粒体和微粒体变化。