Das I J, Downes M B, Corn B W, Curran W J, Werner-Wasik M, Andrews D W
Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA. I_Das/FCCC.edu
Radiother Oncol. 1996 Jan;38(1):61-8. doi: 10.1016/0167-8140(95)01674-0.
A stereotactic radiosurgery and radiotherapy (SRS/SRT) system on a dedicated Varian Clinac-600SR linear accelerator with Brown-Roberts-Wells and Gill-Thomas-Cosman relocatable frames along with the Radionics (RSA) planning system is evaluated. The Clinac-600SR has a single 6-MV beam with the same beam characteristics as that of the mother unit, the Clinac-600C. The primary collimator is a fixed cone projecting to a 10-cm diameter at isocenter. The secondary collimator is a heavily shielded cylindrical collimator attached to the face plate of the primary collimator. The tertiary collimation consists of the actual treatment cones. The cone sizes vary from 12.5 to 40.0 mm diameter. The mechanical stability of the entire system was verified. The variations in isocenter position with table, gantry, and collimator rotation were found to be < 0.5 mm with a compounded accuracy of < or = 1.0 mm. The radiation leakage under the cones was < 1% measured at a depth of 5 cm in a phantom. The beam profiles of all cones in the x and y directions were within +/- 0.5 mm and match with the physical size of the cone. The dosimetric data such as tissue maximum ratio, off-axis ratio, and cone factor were taken using film, diamond detector, and ion chambers. The mechanical and dosimetric characteristics including dose linearity of this unit are presented and found to be suitable for SRS/SRT. The difficulty in absolute dose measurement for small cone is discussed.
对一台配备布朗 - 罗伯茨 - 韦尔斯(Brown-Roberts-Wells)和吉尔 - 托马斯 - 科斯曼(Gill-Thomas-Cosman)可移动框架的专用瓦里安Clinac-600SR直线加速器上的立体定向放射外科和放射治疗(SRS/SRT)系统以及放射电子学(RSA)计划系统进行了评估。Clinac-600SR有一个6兆伏的单束,其束流特性与母机Clinac-600C相同。初级准直器是一个固定圆锥,在等中心处投射直径为10厘米。次级准直器是一个安装在初级准直器面板上的高度屏蔽圆柱形准直器。三级准直由实际的治疗圆锥组成。圆锥尺寸从直径12.5毫米到40.0毫米不等。验证了整个系统的机械稳定性。发现等中心位置随治疗床、机架和准直器旋转的变化小于0.5毫米,复合精度小于或等于1.0毫米。在模体中5厘米深度处测量,圆锥下的辐射泄漏小于1%。所有圆锥在x和y方向的束流轮廓在±0.5毫米以内,且与圆锥的物理尺寸匹配。使用胶片、金刚石探测器和电离室获取组织最大剂量比、离轴剂量比和圆锥因子等剂量学数据。给出了该装置包括剂量线性在内的机械和剂量学特性,发现其适用于SRS/SRT。讨论了小圆锥绝对剂量测量的困难。