Richman A, Abbey H
Drug Alcohol Depend. 1977 Jul;2(4):221-37. doi: 10.1016/0376-8716(77)90001-1.
Smooth unimodal skewed distributions, sometimes referred to as "epidemic-like" curves, are often used as evidence of time to time changes in incidence. Data on year of onset from groups of treated heroin addicts are generally alleged to reflect incidence, and this distribution is used to evaluate effectiveness and predict future needs. This paper describes the development of simple demographic models which demonstrate the production of epidemic-like curves without changes in incidence, ascertainment or duration of disorder. These graphic models are relevant to other non-infectious disorders where there is continuing exposure to the etiologic agents and where intervals between onset and ascertainment are not uniformly distributed.
平滑的单峰偏态分布,有时被称为“类流行”曲线,常被用作发病率随时间变化的证据。来自接受治疗的海洛因成瘾者群体的发病年份数据通常被认为反映了发病率,并且这种分布被用于评估疗效和预测未来需求。本文描述了简单人口模型的发展,这些模型表明在发病率、确诊率或疾病持续时间没有变化的情况下会产生类流行曲线。这些图形模型适用于其他非传染性疾病,在这些疾病中,病因持续存在,发病与确诊之间的间隔并非均匀分布。